Washington Manual of Medical Therapeutics
Principles of Stem Cell Transplantation
Principles of Stem Cell Transplantation is a topic covered in the Washington Manual of Medical Therapeutics.
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Background
- Hematopoietic stem cell transplantation involves the infusion of either allogeneic (different donor) or autologous (patient’s own) stem cells following administration of chemotherapy and/or radiation.
- Autologous transplantation involves collection, cryopreservation, and reinfusion of a patient’s own stem cells. This allows administration of myeloablative doses of chemotherapy with the intent of maximizing the efficacy of therapy.
- Allogeneic transplantation refers to the infusion of stem cells collected from either HLA-matched or mismatched donors. In addition to facilitating the administration of high doses of chemotherapy, allogeneic transplantation also allows for an immunologic effect mediated by donor T and natural killer cells (graft-versus-tumor effect).
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Citation
Williams, Dominique, et al., editors. "Principles of Stem Cell Transplantation." Washington Manual of Medical Therapeutics, 35th ed., Wolters Kluwer Health, 2016. Washington Manual, www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602039/all/Principles_of_Stem_Cell_Transplantation.
Principles of Stem Cell Transplantation. In: Williams D, Ramgopal R, Gdowski M, et al, eds. Washington Manual of Medical Therapeutics. 35th ed. Wolters Kluwer Health; 2016. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602039/all/Principles_of_Stem_Cell_Transplantation. Accessed October 21, 2019.
Principles of Stem Cell Transplantation. (2016). In Williams, D., Ramgopal, R., Gdowski, M., Dretler, A., & Bhat, P. (Eds.), Washington Manual of Medical Therapeutics. Available from https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602039/all/Principles_of_Stem_Cell_Transplantation
Principles of Stem Cell Transplantation [Internet]. In: Williams D, Ramgopal R, Gdowski M, Dretler A, Bhat P, editors. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. [cited 2019 October 21]. Available from: https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602039/all/Principles_of_Stem_Cell_Transplantation.
* Article titles in AMA citation format should be in sentence-case
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T1 - Principles of Stem Cell Transplantation
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ED - Gdowski,Mark,
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ED - Bhat,Pavat,
BT - Washington Manual of Medical Therapeutics
UR - https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602039/all/Principles_of_Stem_Cell_Transplantation
PB - Wolters Kluwer Health
ET - 35
DB - Washington Manual
DP - Unbound Medicine
ER -