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Febrile Neutropenia

Febrile Neutropenia is a topic covered in the Washington Manual of Medical Therapeutics.

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  • FN is defined as an absolute neutrophil count (ANC) of <500/μL, with a single core temperature of >38.3°C or a persistent temperature (>1 hour) of >38.0°C.
  • Risk of FN is proportional to the duration of neutropenia.
  • Although most solid tumor chemotherapy regimens are associated with a brief (<5 days) duration of neutropenia, neutropenia with leukemia and transplantation regimens can be more persistent.
  • Risk is also increased with regimens that cause mucositis (inflammation and ulceration of the oral and GI mucosa).

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Williams, Dominique, et al., editors. "Febrile Neutropenia." Washington Manual of Medical Therapeutics, 35th ed., Wolters Kluwer Health, 2016. Washington Manual, www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602053/all/Febrile_Neutropenia.
Febrile Neutropenia. In: Williams D, Ramgopal R, Gdowski M, et al, eds. Washington Manual of Medical Therapeutics. 35th ed. Wolters Kluwer Health; 2016. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602053/all/Febrile_Neutropenia. Accessed July 16, 2019.
Febrile Neutropenia. (2016). In Williams, D., Ramgopal, R., Gdowski, M., Dretler, A., & Bhat, P. (Eds.), Washington Manual of Medical Therapeutics. Available from https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602053/all/Febrile_Neutropenia
Febrile Neutropenia [Internet]. In: Williams D, Ramgopal R, Gdowski M, Dretler A, Bhat P, editors. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. [cited 2019 July 16]. Available from: https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602053/all/Febrile_Neutropenia.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Febrile Neutropenia ID - 602053 ED - Williams,Dominique, ED - Ramgopal,Rajeev, ED - Gdowski,Mark, ED - Dretler,Alexandra, ED - Bhat,Pavat, BT - Washington Manual of Medical Therapeutics UR - https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602053/all/Febrile_Neutropenia PB - Wolters Kluwer Health ET - 35 DB - Washington Manual DP - Unbound Medicine ER -