General Principles

  • Osteoporosis is defined as a decrease in the amount of bone (mainly trabecular bone), leading to a decrease in its structural integrity and increase in the risk of fractures.
  • The relative risk of osteopenia in cholestasis is 4.4 times greater than the general population, matched for age and gender. It is particularly common in cholestasis caused by PBC.1

There's more to see -- the rest of this topic is available only to subscribers.