Osteoporosis is a topic covered in the Washington Manual of Medical Therapeutics.

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Washington Manual

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General Principles

  • Osteoporosis is defined as a decrease in the amount of bone (mainly trabecular bone), leading to a decrease in its structural integrity and increase in the risk of fractures.
  • The relative risk of osteopenia in cholestasis is 4.4 times greater than the general population, matched for age and gender. It is particularly common in cholestasis because of PBC.1

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