Acute Rejection, Liver

General Principles

  • Many liver transplant recipients are maintained on minimal immunosuppression. Acute rejection typically occurs within the first 3 months after transplant and often in the first 2 weeks after the operation. Acute rejection in the liver is generally reversible and does not portend as serious adverse outcomes as in other organs. Recurrent viral hepatitis is a much more frequent and morbid problem.
  • Liver transplant recipients commonly experience acute allograft rejection, with at least 60% having one episode.

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