Washington Manual of Medical Therapeutics
Hepatic Vein Thrombosis
General Principles
Hepatic vein thrombosis (HVT), also known as Budd–Chiari syndrome, causes hepatic venous outflow obstruction. It has multiple etiologies and a variety of clinical consequences.
- Thrombosis is the main factor leading to obstruction of the hepatic venous system, frequently in association with myeloproliferative disorders (i.e., polycythemia vera), antiphospholipid antibody syndrome, paroxysmal nocturnal hemoglobinuria, factor V Leiden, protein C and S deficiency, Jak-2 mutation, and contraceptive use.
- Membranous obstruction of the inferior vena cava (IVC) and stenosis of the IVC anastomosis after liver transplantation are conditions that present clinically similar to HVT.
- Some cases are idiopathic.
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Citation
Bhat, Pavat, et al., editors. "Hepatic Vein Thrombosis." Washington Manual of Medical Therapeutics, 35th ed., Wolters Kluwer Health, 2016. The Washington Manual, www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602089/all/Hepatic_Vein_Thrombosis.
Hepatic Vein Thrombosis. In: Bhat PP, Dretler AA, Gdowski MM, et al, eds. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602089/all/Hepatic_Vein_Thrombosis. Accessed May 28, 2023.
Hepatic Vein Thrombosis. (2016). In Bhat, P., Dretler, A., Gdowski, M., Ramgopal, R., & Williams, D. (Eds.), Washington Manual of Medical Therapeutics (35th ed.). Wolters Kluwer Health. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602089/all/Hepatic_Vein_Thrombosis
Hepatic Vein Thrombosis [Internet]. In: Bhat PP, Dretler AA, Gdowski MM, Ramgopal RR, Williams DD, editors. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. [cited 2023 May 28]. Available from: https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602089/all/Hepatic_Vein_Thrombosis.
* Article titles in AMA citation format should be in sentence-case
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T1 - Hepatic Vein Thrombosis
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ED - Williams,Dominique,
ED - Bhat,Pavat,
ED - Dretler,Alexandra,
ED - Gdowski,Mark,
ED - Ramgopal,Rajeev,
BT - Washington Manual of Medical Therapeutics
UR - https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602089/all/Hepatic_Vein_Thrombosis
PB - Wolters Kluwer Health
ET - 35
DB - The Washington Manual
DP - Unbound Medicine
ER -
