Postinfectious Glomerulonephropathy
General Principles
- Postinfectious glomerulonephropathy classically presents as nephritic syndrome, with hematuria, hypertension, edema, and renal insufficiency. Proteinuria may be present and is usually in the subnephrotic range.
- This entity is classically associated with streptococcal infection, which typically affects children under the age of 10, after a latent period of 2–4 weeks from onset of pharyngitis or skin infection. However, bacterial endocarditis, visceral abscesses, and ventriculoperitoneal shunt infections can also lead to this immune complex–mediated disease.
- Low complement levels are usually seen. ASO titers may be elevated serially, as may anti-DNase B antibodies in streptococcal-associated disease.
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Citation
Bhat, Pavat, et al., editors. "Postinfectious Glomerulonephropathy." Washington Manual of Medical Therapeutics, 35th ed., Wolters Kluwer Health, 2016. The Washington Manual, www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602117/all/Postinfectious_Glomerulonephropathy.
Postinfectious Glomerulonephropathy. In: Bhat PP, Dretler AA, Gdowski MM, et al, eds. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602117/all/Postinfectious_Glomerulonephropathy. Accessed September 26, 2023.
Postinfectious Glomerulonephropathy. (2016). In Bhat, P., Dretler, A., Gdowski, M., Ramgopal, R., & Williams, D. (Eds.), Washington Manual of Medical Therapeutics (35th ed.). Wolters Kluwer Health. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602117/all/Postinfectious_Glomerulonephropathy
Postinfectious Glomerulonephropathy [Internet]. In: Bhat PP, Dretler AA, Gdowski MM, Ramgopal RR, Williams DD, editors. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. [cited 2023 September 26]. Available from: https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602117/all/Postinfectious_Glomerulonephropathy.
* Article titles in AMA citation format should be in sentence-case
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