Deposition Disorders/Dysproteinemias

Deposition Disorders/Dysproteinemias is a topic covered in the Washington Manual of Medical Therapeutics.

To view the entire topic, please or purchase a subscription.

The Washington Manual of Medical Therapeutics helps you diagnose and treat hundreds of medical conditions. Consult clinical recommendations from a resource that has been trusted on the wards for 50+ years. Explore these free sample topics:

Washington Manual

-- The first section of this topic is shown below --

General Principles

Dysproteinemias—including those observed in multiple myeloma—include amyloidosis, light chain deposition disease (LCDD), and heavy chain deposition disease (HCDD). These disorders can affect the kidney in a variety of ways, including glomerular or tubular deposition, formation of insoluble protein casts in the tubules (micro-obstructive cast nephropathy), or through hypercalcemia and volume depletion. Glomerular deposition is typically associated with heavy proteinuria due to overflow as well as disruption of filtration barrier integrity.

-- To view the remaining sections of this topic, please or purchase a subscription --