Coccidioidomycosis is a topic covered in the Washington Manual of Medical Therapeutics.

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General Principles

  • Coccidioides immitis is a dimorphic fungus that is endemic to the southwestern United States and Central America.
  • Disease is usually a self-limited pulmonary syndrome, responsible for up to 25% of all community-acquired pneumonia in endemic regions. Less-common manifestations are chronic pulmonary illness and disseminated disease, which can affect the meninges, bones, joints, and skin. Risk factors for development of severe or disseminated disease include immunocompromising conditions, African or Filipino ancestry, diabetes, and pregnancy.

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