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Constrictive Pericarditis

Constrictive Pericarditis is a topic covered in the Washington Manual of Medical Therapeutics.

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General Principles

Constrictive pericarditis, as a cause of right-sided heart failure (HF), often goes undiagnosed. It is often difficult to distinguish from restrictive cardiomyopathies (RCMs). Multiple imaging modalities and invasive hemodynamics are often needed to confirm the diagnosis.

Etiology

  • Common
    • Idiopathic, viral pericarditis (chronic or recurrent), postcardiotomy, chest irradiation
  • Less common
    • Autoimmune connective tissue disorders, end-stage renal disease, uremia, malignancy (e.g., breast, lung, lymphoma), tuberculosis (most common cause in developing countries)

Pathophysiology

In the setting of chronic inflammation, the pericardial layers become thickened, scarred, and calcified; the pericardial space is obliterated, and the pericardium becomes noncompliant, which impairs ventricular filling and leads to an equalization of pressures in all four chambers and subsequent HF symptoms.

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Citation

Williams, Dominique, et al., editors. "Constrictive Pericarditis." Washington Manual of Medical Therapeutics, 35th ed., Wolters Kluwer Health, 2016. Washington Manual, www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602167/all/Constrictive_Pericarditis.
Constrictive Pericarditis. In: Williams D, Ramgopal R, Gdowski M, et al, eds. Washington Manual of Medical Therapeutics. 35th ed. Wolters Kluwer Health; 2016. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602167/all/Constrictive_Pericarditis. Accessed May 26, 2019.
Constrictive Pericarditis. (2016). In Williams, D., Ramgopal, R., Gdowski, M., Dretler, A., & Bhat, P. (Eds.), Washington Manual of Medical Therapeutics. Available from https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602167/all/Constrictive_Pericarditis
Constrictive Pericarditis [Internet]. In: Williams D, Ramgopal R, Gdowski M, Dretler A, Bhat P, editors. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. [cited 2019 May 26]. Available from: https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602167/all/Constrictive_Pericarditis.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Constrictive Pericarditis ID - 602167 ED - Williams,Dominique, ED - Ramgopal,Rajeev, ED - Gdowski,Mark, ED - Dretler,Alexandra, ED - Bhat,Pavat, BT - Washington Manual of Medical Therapeutics UR - https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602167/all/Constrictive_Pericarditis PB - Wolters Kluwer Health ET - 35 DB - Washington Manual DP - Unbound Medicine ER -