Chronic Renal Insufficiency and ESRD

Chronic Renal Insufficiency and ESRD is a topic covered in the Washington Manual of Medical Therapeutics.

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General Principles

  • Chronic renal insufficiency (CRI) is an independent risk factor for perioperative cardiac complications, so all patients with renal disease need appropriate cardiac risk stratification.1
  • Patients with ESRD have a substantial mortality risk when undergoing surgery.2
  • Most general anesthetic agents have no appreciable nephrotoxicity or effect on renal function other than that mediated through hemodynamic changes.3

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General Principles

  • Chronic renal insufficiency (CRI) is an independent risk factor for perioperative cardiac complications, so all patients with renal disease need appropriate cardiac risk stratification.1
  • Patients with ESRD have a substantial mortality risk when undergoing surgery.2
  • Most general anesthetic agents have no appreciable nephrotoxicity or effect on renal function other than that mediated through hemodynamic changes.3

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