Nutritional Deficiencies

Nutritional Deficiencies is a topic covered in the Washington Manual of Medical Therapeutics.

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General Principles

Any condition that blocks bile excretion (at the level of the liver cell or the biliary ducts) is defined as cholestasis. Laboratory evidence of cholestasis includes elevated ALP and bilirubin.

  • Nutritional deficiencies result from fat malabsorption.
  • Fat-soluble vitamin deficiency (vitamins A, D, E, and K) is often present in advanced cholestasis and is particularly common in patients with steatorrhea.

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