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Malignant Hypercalcemia

Malignant Hypercalcemia is a topic covered in the Washington Manual of Medical Therapeutics.

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  • Malignant hypercalcemia is a common paraneoplastic syndrome and occurs in nearly 10%–20% of cancer patients.
  • A serum total calcium level of >10.5 g/dL is generally considered elevated. Measuring ionized calcium can be necessary and helpful in patients with abnormal serum albumin levels.
  • Osteolysis and humoral hypercalcemia through tumor production of parathyroid hormone (PTH), PTH-related protein (PTHrP), or vitamin D analogues are the predominant mechanisms of hypercalcemia.

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Citation

Williams, Dominique, et al., editors. "Malignant Hypercalcemia." Washington Manual of Medical Therapeutics, 35th ed., Wolters Kluwer Health, 2016. Washington Manual, www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602229/all/Malignant_Hypercalcemia.
Malignant Hypercalcemia. In: Williams D, Ramgopal R, Gdowski M, et al, eds. Washington Manual of Medical Therapeutics. 35th ed. Wolters Kluwer Health; 2016. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602229/all/Malignant_Hypercalcemia. Accessed July 18, 2019.
Malignant Hypercalcemia. (2016). In Williams, D., Ramgopal, R., Gdowski, M., Dretler, A., & Bhat, P. (Eds.), Washington Manual of Medical Therapeutics. Available from https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602229/all/Malignant_Hypercalcemia
Malignant Hypercalcemia [Internet]. In: Williams D, Ramgopal R, Gdowski M, Dretler A, Bhat P, editors. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. [cited 2019 July 18]. Available from: https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602229/all/Malignant_Hypercalcemia.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Malignant Hypercalcemia ID - 602229 ED - Williams,Dominique, ED - Ramgopal,Rajeev, ED - Gdowski,Mark, ED - Dretler,Alexandra, ED - Bhat,Pavat, BT - Washington Manual of Medical Therapeutics UR - https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602229/all/Malignant_Hypercalcemia PB - Wolters Kluwer Health ET - 35 DB - Washington Manual DP - Unbound Medicine ER -