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Acute Pancreatitis

Acute Pancreatitis is a topic covered in the Washington Manual of Medical Therapeutics.

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General Principles

Definition

Acute pancreatitis consists of inflammation of the pancreas and peripancreatic tissue from activation of potent pancreatic enzymes within the pancreas, particularly trypsin.

Etiology

The most common causes are alcohol and gallstone disease, accounting for 75–80% of all cases. Less common causes include abdominal trauma, hypercalcemia, hypertriglyceridemia, and a variety of drugs. Post–endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis occurs in 5–10% of patients undergoing ERCP; prophylaxis with rectal NSAIDs or topical epinephrine and placement of prophylactic pancreatic duct stents can help prevent post-ERCP pancreatitis (Aliment Pharmacol Ther 2013;38:1325  [PMID:24138390]).

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Citation

Williams, Dominique, et al., editors. "Acute Pancreatitis." Washington Manual of Medical Therapeutics, 35th ed., Wolters Kluwer Health, 2016. Washington Manual, www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602291/4/Acute_Pancreatitis.
Acute Pancreatitis. In: Williams D, Ramgopal R, Gdowski M, et al, eds. Washington Manual of Medical Therapeutics. 35th ed. Wolters Kluwer Health; 2016. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602291/4/Acute_Pancreatitis. Accessed June 20, 2019.
Acute Pancreatitis. (2016). In Williams, D., Ramgopal, R., Gdowski, M., Dretler, A., & Bhat, P. (Eds.), Washington Manual of Medical Therapeutics. Available from https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602291/4/Acute_Pancreatitis
Acute Pancreatitis [Internet]. In: Williams D, Ramgopal R, Gdowski M, Dretler A, Bhat P, editors. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. [cited 2019 June 20]. Available from: https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602291/4/Acute_Pancreatitis.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Acute Pancreatitis ID - 602291 ED - Williams,Dominique, ED - Ramgopal,Rajeev, ED - Gdowski,Mark, ED - Dretler,Alexandra, ED - Bhat,Pavat, BT - Washington Manual of Medical Therapeutics UR - https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602291/4/Acute_Pancreatitis PB - Wolters Kluwer Health ET - 35 DB - Washington Manual DP - Unbound Medicine ER -