Ethambutol

Ethambutol is a topic covered in the Washington Manual of Medical Therapeutics.

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General Principles

  • Ethambutol (15–25 mg/kg PO q24h or 50–75 mg/kg PO twice a week; maximum, 2.4 g/dose) is bacteriostatic and inhibits arabinosyltransferase (involved in cell wall synthesis).
  • Doses should be reduced in the presence of renal dysfunction.

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General Principles

  • Ethambutol (15–25 mg/kg PO q24h or 50–75 mg/kg PO twice a week; maximum, 2.4 g/dose) is bacteriostatic and inhibits arabinosyltransferase (involved in cell wall synthesis).
  • Doses should be reduced in the presence of renal dysfunction.

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