Necrotizing Fasciitis

Necrotizing Fasciitis is a topic covered in the Washington Manual of Medical Therapeutics.

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General Principles

  • This is an infectious disease emergency with high mortality manifested by extensive soft-tissue infection and thrombosis of the microcirculation with resulting necrosis. Infection spreads quickly along fascial planes and may be associated with sepsis or TSS. Fournier gangrene is necrotizing fasciitis of the perineum.
  • Bacterial etiology is either mixed (aerobic and anaerobic organisms) or monomicrobial (GABHS or S. aureus, including community-acquired MRSA).

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General Principles

  • This is an infectious disease emergency with high mortality manifested by extensive soft-tissue infection and thrombosis of the microcirculation with resulting necrosis. Infection spreads quickly along fascial planes and may be associated with sepsis or TSS. Fournier gangrene is necrotizing fasciitis of the perineum.
  • Bacterial etiology is either mixed (aerobic and anaerobic organisms) or monomicrobial (GABHS or S. aureus, including community-acquired MRSA).

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