Penicillins
Penicillins is a topic covered in the Washington Manual of Medical Therapeutics.
To view the entire topic, please log in or purchase a subscription.
The Washington Manual is an award-winning, complete mobile solution for nurses and students. Look up information on diseases, tests, and procedures; then consult the database with 5,000+ drugs or refer to 65,000+ dictionary terms. Explore these free sample topics:
-- The first section of this topic is shown below --
General Principles
- Penicillins (PCNs) irreversibly bind PCN-binding proteins (PBPs) in the bacterial cell wall, ultimately causing osmotic rupture and death. Acquired resistance in many bacterial species through alterations in PBPs or expression of hydrolytic enzymes has limited their use.
- PCNs remain among the drugs of choice for syphilis and infections caused by PCN-sensitive streptococci and enterococci, methicillin-sensitive Staphylococcus aureus (MSSA), Listeria monocytogenes, Pasteurella multocida, and Actinomyces.
-- To view the remaining sections of this topic, please log in or purchase a subscription --
General Principles
- Penicillins (PCNs) irreversibly bind PCN-binding proteins (PBPs) in the bacterial cell wall, ultimately causing osmotic rupture and death. Acquired resistance in many bacterial species through alterations in PBPs or expression of hydrolytic enzymes has limited their use.
- PCNs remain among the drugs of choice for syphilis and infections caused by PCN-sensitive streptococci and enterococci, methicillin-sensitive Staphylococcus aureus (MSSA), Listeria monocytogenes, Pasteurella multocida, and Actinomyces.
There's more to see -- the rest of this topic is available only to subscribers.
Citation
Bhat, Pavat, et al., editors. "Penicillins." Washington Manual of Medical Therapeutics, 35th ed., Wolters Kluwer Health, 2016. Washington Manual Redesign, www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602328/all/Penicillins.
Penicillins. In: Bhat PP, Dretler AA, Gdowski MM, et al, eds. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602328/all/Penicillins. Accessed January 31, 2023.
Penicillins. (2016). In Bhat, P., Dretler, A., Gdowski, M., Ramgopal, R., & Williams, D. (Eds.), Washington Manual of Medical Therapeutics (35th ed.). Wolters Kluwer Health. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602328/all/Penicillins
Penicillins [Internet]. In: Bhat PP, Dretler AA, Gdowski MM, Ramgopal RR, Williams DD, editors. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. [cited 2023 January 31]. Available from: https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602328/all/Penicillins.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Penicillins
ID - 602328
ED - Williams,Dominique,
ED - Bhat,Pavat,
ED - Dretler,Alexandra,
ED - Gdowski,Mark,
ED - Ramgopal,Rajeev,
BT - Washington Manual of Medical Therapeutics
UR - https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602328/all/Penicillins
PB - Wolters Kluwer Health
ET - 35
DB - Washington Manual Redesign
DP - Unbound Medicine
ER -