Cryptococcosis
Cryptococcosis is a topic covered in the Washington Manual of Medical Therapeutics.
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General Principles
- Cryptococcus neoformans is a ubiquitous yeast associated with soil and pigeon excrement.
- Disease is principally meningeal (headache and mental status changes) and pulmonary (ranging from asymptomatic nodular disease to fulminant respiratory failure). Disseminated disease can involve any organ with predilection for the CNS, lungs, skin (umbilicated lesions mimicking molluscum), bone, and prostate.
- Infection typically affects patients with impaired cellular immunity and carries high morbidity and mortality. Although rare, infection in patients with end-stage liver disease has been associated with higher mortality compared to HIV-positive patients and should be considered when symptoms of cryptococcosis are present.
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General Principles
- Cryptococcus neoformans is a ubiquitous yeast associated with soil and pigeon excrement.
- Disease is principally meningeal (headache and mental status changes) and pulmonary (ranging from asymptomatic nodular disease to fulminant respiratory failure). Disseminated disease can involve any organ with predilection for the CNS, lungs, skin (umbilicated lesions mimicking molluscum), bone, and prostate.
- Infection typically affects patients with impaired cellular immunity and carries high morbidity and mortality. Although rare, infection in patients with end-stage liver disease has been associated with higher mortality compared to HIV-positive patients and should be considered when symptoms of cryptococcosis are present.
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Citation
Bhat, Pavat, et al., editors. "Cryptococcosis." Washington Manual of Medical Therapeutics, 35th ed., Wolters Kluwer Health, 2016. The Washington Manual, www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602335/all/Cryptococcosis.
Cryptococcosis. In: Bhat PP, Dretler AA, Gdowski MM, et al, eds. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602335/all/Cryptococcosis. Accessed February 1, 2023.
Cryptococcosis. (2016). In Bhat, P., Dretler, A., Gdowski, M., Ramgopal, R., & Williams, D. (Eds.), Washington Manual of Medical Therapeutics (35th ed.). Wolters Kluwer Health. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602335/all/Cryptococcosis
Cryptococcosis [Internet]. In: Bhat PP, Dretler AA, Gdowski MM, Ramgopal RR, Williams DD, editors. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. [cited 2023 February 01]. Available from: https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602335/all/Cryptococcosis.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Cryptococcosis
ID - 602335
ED - Williams,Dominique,
ED - Bhat,Pavat,
ED - Dretler,Alexandra,
ED - Gdowski,Mark,
ED - Ramgopal,Rajeev,
BT - Washington Manual of Medical Therapeutics
UR - https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602335/all/Cryptococcosis
PB - Wolters Kluwer Health
ET - 35
DB - The Washington Manual
DP - Unbound Medicine
ER -