The Washington Manual of Medical Therapeutics helps you diagnose and treat hundreds of medical conditions. Consult clinical recommendations from a resource that has been trusted on the wards for 50+ years. Explore these free sample topics:
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- Human bites, particularly clenched-fist injuries, are prone to infection and other complications. The normal oral flora of humans includes viridans streptococci, staphylococci, Bacteroides spp., Fusobacterium spp., peptostreptococci, and Eikenella corrodens.
- Prophylaxis with amoxicillin-clavulanate 875 mg/125 mg PO q12h for 5 days is recommended for uninfected wounds.
- Infected wounds may require parenteral therapy, such as ampicillin-sulbactam 1.5 g IV q6h, cefoxitin 2 g IV q8h, or ticarcillin-clavulanate 3.1 g IV q6h for 1–2 weeks. Therapy should be extended to 4–6 weeks if osteomyelitis is present.