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Gastroparesis

Gastroparesis is a topic covered in the Washington Manual of Medical Therapeutics.

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General Principles

Definition

Gastroparesis consists of abnormally delayed emptying of stomach contents into the small bowel in the absence of gastric outlet obstruction or ulceration, usually as a result of damage to the nerves or smooth muscle involved in gastric emptying.

Etiology

  • Mechanical obstruction should always be excluded.
  • In addition to evaluating for acute metabolic derangements and potential offending medications (narcotics, anticholinergic agents, chemotherapeutic agents, glucagon-like peptide-1 and amylin analogs), patients with gastroparesis should be screened for diabetes mellitus, thyroid dysfunction, neurologic disease, prior gastric or bariatric surgery, and autoimmune disorders (e.g., scleroderma).
  • If no predisposing cause is identified, gastroparesis is designated idiopathic.

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Citation

Williams, Dominique, et al., editors. "Gastroparesis." Washington Manual of Medical Therapeutics, 35th ed., Wolters Kluwer Health, 2016. Washington Manual, www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602384/all/Gastroparesis.
Gastroparesis. In: Williams D, Ramgopal R, Gdowski M, et al, eds. Washington Manual of Medical Therapeutics. 35th ed. Wolters Kluwer Health; 2016. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602384/all/Gastroparesis. Accessed May 24, 2019.
Gastroparesis. (2016). In Williams, D., Ramgopal, R., Gdowski, M., Dretler, A., & Bhat, P. (Eds.), Washington Manual of Medical Therapeutics. Available from https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602384/all/Gastroparesis
Gastroparesis [Internet]. In: Williams D, Ramgopal R, Gdowski M, Dretler A, Bhat P, editors. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. [cited 2019 May 24]. Available from: https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602384/all/Gastroparesis.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Gastroparesis ID - 602384 ED - Williams,Dominique, ED - Ramgopal,Rajeev, ED - Gdowski,Mark, ED - Dretler,Alexandra, ED - Bhat,Pavat, BT - Washington Manual of Medical Therapeutics UR - https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602384/all/Gastroparesis PB - Wolters Kluwer Health ET - 35 DB - Washington Manual DP - Unbound Medicine ER -