Ovarian Cancer

Ovarian Cancer is a topic covered in the Washington Manual of Medical Therapeutics.

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Epidemiology

Ovarian cancer is the leading cause of gynecologic mortality in the United States, with 14,070 deaths estimated in 2018. Risk factors include early menarche, late menopause, nulligravidity, family history, and familial syndromes including patients with BRCA1 and BRCA2 mutations and Lynch syndrome. Oral contraception use and pregnancy are associated with a low risk of ovarian cancer, suggesting a role for ovulation in malignant transformation.

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