Magnesium

Magnesium is a topic covered in the Washington Manual of Medical Therapeutics.

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  • Magnesium plays an important role in neuromuscular function.
  • Approximately 60% of body magnesium is stored in bone, and most of the remainder is found in cells. Only 1% is in the ECF. As a result, the serum magnesium is a poor predictor of intracellular and total body stores and may grossly underestimate total magnesium deficits.
  • The main determinant of magnesium balance is the magnesium concentration itself, which directly influences renal excretion. Hypomagnesemia stimulates tubular reabsorption of magnesium, whereas hypermagnesemia inhibits it.

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  • Magnesium plays an important role in neuromuscular function.
  • Approximately 60% of body magnesium is stored in bone, and most of the remainder is found in cells. Only 1% is in the ECF. As a result, the serum magnesium is a poor predictor of intracellular and total body stores and may grossly underestimate total magnesium deficits.
  • The main determinant of magnesium balance is the magnesium concentration itself, which directly influences renal excretion. Hypomagnesemia stimulates tubular reabsorption of magnesium, whereas hypermagnesemia inhibits it.

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