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Cancer Pain

Cancer Pain is a topic covered in the Washington Manual of Medical Therapeutics.

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  • The two main mechanisms for pain are nociceptive (somatic or visceral) and neuropathic.
    • Nociceptive pain is caused by stimulation of pain receptors and neuropathic pain by direct injury to the peripheral nervous system or CNS.
    • Somatic pain typically occurs with bone metastases, musculoskeletal inflammation, or after surgery and is characterized by a well-localized, dull, or aching pain.
    • Visceral pain results from tumor infiltration and compression or distention of viscera and is described as diffuse, deep, squeezing, and pressure-like sensation.
    • Neuropathic pain occurs because of tumor infiltration of peripheral nerves, roots, or spinal cord, as well as chemical injury caused by chemotherapy, radiotherapy, or surgery. This pain is described as a sharp or burning sensation.
  • These three types of pain may occur alone or in combination in the same patient.
  • Cancer pain in adults may be classified into three levels on the basis of a 0–10 numerical scale: mild pain (1–3), moderate pain (4–6), and severe pain (7–10).

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Williams, Dominique, et al., editors. "Cancer Pain." Washington Manual of Medical Therapeutics, 35th ed., Wolters Kluwer Health, 2016. Washington Manual, www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602434/all/Cancer_Pain.
Cancer Pain. In: Williams D, Ramgopal R, Gdowski M, et al, eds. Washington Manual of Medical Therapeutics. 35th ed. Wolters Kluwer Health; 2016. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602434/all/Cancer_Pain. Accessed July 17, 2019.
Cancer Pain. (2016). In Williams, D., Ramgopal, R., Gdowski, M., Dretler, A., & Bhat, P. (Eds.), Washington Manual of Medical Therapeutics. Available from https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602434/all/Cancer_Pain
Cancer Pain [Internet]. In: Williams D, Ramgopal R, Gdowski M, Dretler A, Bhat P, editors. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. [cited 2019 July 17]. Available from: https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602434/all/Cancer_Pain.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Cancer Pain ID - 602434 ED - Williams,Dominique, ED - Ramgopal,Rajeev, ED - Gdowski,Mark, ED - Dretler,Alexandra, ED - Bhat,Pavat, BT - Washington Manual of Medical Therapeutics UR - https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602434/all/Cancer_Pain PB - Wolters Kluwer Health ET - 35 DB - Washington Manual DP - Unbound Medicine ER -