Fulminant Hepatic Failure
Fulminant Hepatic Failure is a topic covered in the Washington Manual of Medical Therapeutics.
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General Principles
- FHF is a condition that includes evidence of a combination of coagulation abnormalities and any degree of mental alteration (encephalopathy) in a patient without preexisting liver disease and with an illness of <26 weeks in duration.
- In 20% of cases, no clear cause is identified. Acetaminophen hepatotoxicity and viral hepatitis are the most common causes of FHF. Other causes include AIH, drug and toxin exposure, ischemia, acute fatty liver of pregnancy, WD, and Budd-Chiari syndrome.
- Acute inflammation with varying degrees of necrosis and collapse of the liver’s architectural framework are the typical histologic changes seen in FHF.
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Citation
Williams, Dominique, et al., editors. "Fulminant Hepatic Failure." Washington Manual of Medical Therapeutics, 35th ed., Wolters Kluwer Health, 2016. Washington Manual, www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602468/all/Fulminant_Hepatic_Failure.
Fulminant Hepatic Failure. In: Williams D, Ramgopal R, Gdowski M, et al, eds. Washington Manual of Medical Therapeutics. 35th ed. Wolters Kluwer Health; 2016. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602468/all/Fulminant_Hepatic_Failure. Accessed December 6, 2019.
Fulminant Hepatic Failure. (2016). In Williams, D., Ramgopal, R., Gdowski, M., Dretler, A., & Bhat, P. (Eds.), Washington Manual of Medical Therapeutics. Available from https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602468/all/Fulminant_Hepatic_Failure
Fulminant Hepatic Failure [Internet]. In: Williams D, Ramgopal R, Gdowski M, Dretler A, Bhat P, editors. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. [cited 2019 December 06]. Available from: https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602468/all/Fulminant_Hepatic_Failure.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Fulminant Hepatic Failure
ID - 602468
ED - Williams,Dominique,
ED - Ramgopal,Rajeev,
ED - Gdowski,Mark,
ED - Dretler,Alexandra,
ED - Bhat,Pavat,
BT - Washington Manual of Medical Therapeutics
UR - https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602468/all/Fulminant_Hepatic_Failure
PB - Wolters Kluwer Health
ET - 35
DB - Washington Manual
DP - Unbound Medicine
ER -