The Washington Manual of Medical Therapeutics helps you diagnose and treat hundreds of medical conditions. Consult clinical recommendations from a resource that has been trusted on the wards for 50+ years. Explore these free sample topics:
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- Botulism results from intoxication with botulinum toxin, produced by the anaerobic gram-positive bacillus Clostridium botulinum.
- Modes of acquisition include ingestion of the neurotoxin from improperly canned food and contamination of wounds with C. botulinum from the soil. Inhalational botulism could result from an intentional release of aerosolized toxin.
- Mortality is low when botulism is recognized early but may be very high in the setting of mass exposure and limited access to mechanical ventilation equipment.