Washington Manual of Medical Therapeutics
Tetracyclines
Tetracyclines is a topic covered in the Washington Manual of Medical Therapeutics.
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General Principles
- Tetracyclines are bacteriostatic antibiotics that bind to the 30S ribosomal subunit and block protein synthesis.
- These agents have unique roles in the treatment of Rickettsia, Ehrlichia, Chlamydia, and Mycoplasma infections. They are used as therapy for most tick-borne infections and Lyme disease–related arthritis, alternate therapy for syphilis, and therapy for P. multocida infections in PCN-allergic patients. Minocycline and doxycycline also have activity against some multidrug-resistant gram-negative pathogens and may be used in this setting based on results of susceptibility testing.
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Citation
Williams, Dominique, et al., editors. "Tetracyclines." Washington Manual of Medical Therapeutics, 35th ed., Wolters Kluwer Health, 2016. Washington Manual, www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602477/all/Tetracyclines.
Tetracyclines. In: Williams D, Ramgopal R, Gdowski M, et al, eds. Washington Manual of Medical Therapeutics. 35th ed. Wolters Kluwer Health; 2016. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602477/all/Tetracyclines. Accessed December 7, 2019.
Tetracyclines. (2016). In Williams, D., Ramgopal, R., Gdowski, M., Dretler, A., & Bhat, P. (Eds.), Washington Manual of Medical Therapeutics. Available from https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602477/all/Tetracyclines
Tetracyclines [Internet]. In: Williams D, Ramgopal R, Gdowski M, Dretler A, Bhat P, editors. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. [cited 2019 December 07]. Available from: https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602477/all/Tetracyclines.
* Article titles in AMA citation format should be in sentence-case
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T1 - Tetracyclines
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ED - Ramgopal,Rajeev,
ED - Gdowski,Mark,
ED - Dretler,Alexandra,
ED - Bhat,Pavat,
BT - Washington Manual of Medical Therapeutics
UR - https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602477/all/Tetracyclines
PB - Wolters Kluwer Health
ET - 35
DB - Washington Manual
DP - Unbound Medicine
ER -