Cervical Cancer

Cervical Cancer is a topic covered in the Washington Manual of Medical Therapeutics.

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Epidemiology and Etiology

Cervical cancer death rates have declined by approximately 80% since 1930 because of the widespread implementation of screening programs, accounting for an estimated 13,800 new cases and 4290 deaths in the US in 2020.1 In countries that lack screening and prevention programs, cervical cancer is the second most common cancer in women. HPV infection is detected in >99% of tumors, most commonly HPV-16 and -18. Other risk factors include early onset of sexual activity, multiple sexual partners, high-risk partners, history of sexually transmitted illness, and chronic immunosuppression.

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Epidemiology and Etiology

Cervical cancer death rates have declined by approximately 80% since 1930 because of the widespread implementation of screening programs, accounting for an estimated 13,800 new cases and 4290 deaths in the US in 2020.1 In countries that lack screening and prevention programs, cervical cancer is the second most common cancer in women. HPV infection is detected in >99% of tumors, most commonly HPV-16 and -18. Other risk factors include early onset of sexual activity, multiple sexual partners, high-risk partners, history of sexually transmitted illness, and chronic immunosuppression.

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