Diabetic Nephropathy

Diabetic Nephropathy is a topic covered in the Washington Manual of Medical Therapeutics.

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General Principles

DN is the most common cause of ESRD in the United States. Albuminuria correlates with the risk of progression and is classified as absent (<30 mg/g Cr), microalbuminuria (30–300 mg/g Cr), or macroalbuminuria (>300 mg/g Cr). Early disease has glomerular hyperfiltration with an elevated GFR, followed by a linear decline that may progress to ESRD.

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General Principles

DN is the most common cause of ESRD in the United States. Albuminuria correlates with the risk of progression and is classified as absent (<30 mg/g Cr), microalbuminuria (30–300 mg/g Cr), or macroalbuminuria (>300 mg/g Cr). Early disease has glomerular hyperfiltration with an elevated GFR, followed by a linear decline that may progress to ESRD.

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