Diabetic Nephropathy

Diabetic Nephropathy is a topic covered in the Washington Manual of Medical Therapeutics.

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General Principles

Diabetic nephropathy (DN) is the most common cause of ESRD in the United States. Risk factors include smoking, family history of ESRD, hypertension, and poor glycemic control. The degree of albuminuria also correlates with the risk of progression to ESRD. Early disease is characterized by glomerular hyperfiltration with an elevated GFR, followed by a linear decline that may progress to ESRD.

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General Principles

Diabetic nephropathy (DN) is the most common cause of ESRD in the United States. Risk factors include smoking, family history of ESRD, hypertension, and poor glycemic control. The degree of albuminuria also correlates with the risk of progression to ESRD. Early disease is characterized by glomerular hyperfiltration with an elevated GFR, followed by a linear decline that may progress to ESRD.

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