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Cephalosporins

Cephalosporins is a topic covered in the Washington Manual of Medical Therapeutics.

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General Principles

  • Cephalosporins exert their bactericidal effect by interfering with cell wall synthesis by the same mechanism as PCNs.
  • These agents are clinically useful because of their broad spectrum of activity and low toxicity profile. All cephalosporins are devoid of clinically significant activity against enterococci when used alone. Within this class, only ceftaroline is active against methicillin-resistant S. aureus (MRSA).

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Citation

Williams, Dominique, et al., editors. "Cephalosporins." Washington Manual of Medical Therapeutics, 35th ed., Wolters Kluwer Health, 2016. Washington Manual, www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602625/all/Cephalosporins.
Cephalosporins. In: Williams D, Ramgopal R, Gdowski M, et al, eds. Washington Manual of Medical Therapeutics. 35th ed. Wolters Kluwer Health; 2016. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602625/all/Cephalosporins. Accessed August 22, 2019.
Cephalosporins. (2016). In Williams, D., Ramgopal, R., Gdowski, M., Dretler, A., & Bhat, P. (Eds.), Washington Manual of Medical Therapeutics. Available from https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602625/all/Cephalosporins
Cephalosporins [Internet]. In: Williams D, Ramgopal R, Gdowski M, Dretler A, Bhat P, editors. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. [cited 2019 August 22]. Available from: https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602625/all/Cephalosporins.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Cephalosporins ID - 602625 ED - Williams,Dominique, ED - Ramgopal,Rajeev, ED - Gdowski,Mark, ED - Dretler,Alexandra, ED - Bhat,Pavat, BT - Washington Manual of Medical Therapeutics UR - https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602625/all/Cephalosporins PB - Wolters Kluwer Health ET - 35 DB - Washington Manual DP - Unbound Medicine ER -