Gastric Cancer

Gastric Cancer is a topic covered in the Washington Manual of Medical Therapeutics.

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Epidemiology and Etiology

The highest incidence rates for gastric cancer are in eastern Asia, Eastern Europe, and South America, whereas the lowest incidence is in North America and Africa. Gastric cancer will account for an estimated 10,800 deaths in 2018 in the United States. Risk factors include H. pylori infection, previous partial gastrectomy for benign ulcer, achlorhydria associated with pernicious anemia, cigarette smoking, and blood group A. Hereditary diffuse gastric cancer is an inherited type of gastric cancer in families with germline CDH1 (E-cadherin) mutations.

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