Disorders of Sodium Concentration

Disorders of Sodium Concentration is a topic covered in the Washington Manual of Medical Therapeutics.

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Hypernatremia and hyponatremia are primarily disorders of water balance or water distribution. The body is designed to withstand both drought and deluge with adaptations to renal water handling and the thirst mechanism. A persistent abnormality in [Na+] thus requires both an initial challenge to water balance as well as a disturbance of the adaptive response.

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Hypernatremia and hyponatremia are primarily disorders of water balance or water distribution. The body is designed to withstand both drought and deluge with adaptations to renal water handling and the thirst mechanism. A persistent abnormality in [Na+] thus requires both an initial challenge to water balance as well as a disturbance of the adaptive response.

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