Ethylene Glycol

Ethylene Glycol is a topic covered in the Washington Manual of Medical Therapeutics.

To view the entire topic, please or .

The Washington Manual of Medical Therapeutics helps you diagnose and treat hundreds of medical conditions. Consult clinical recommendations from a resource that has been trusted on the wards for 50+ years. Explore these free sample topics:

-- The first section of this topic is shown below --

General Principles

Etiology

Ingestions are mostly due to intentional suicide attempts.

Pathophysiology

  • Ethylene glycol is oxidized to glycolic acid and oxalic acid.
  • Glycolate accumulation is responsible for the anion gap metabolic acidosis in ethylene glycol poisoning.
  • Oxalate accumulation is responsible for the development of acute renal failure in ethylene glycol poisoning.1

-- To view the remaining sections of this topic, please or --

General Principles

Etiology

Ingestions are mostly due to intentional suicide attempts.

Pathophysiology

  • Ethylene glycol is oxidized to glycolic acid and oxalic acid.
  • Glycolate accumulation is responsible for the anion gap metabolic acidosis in ethylene glycol poisoning.
  • Oxalate accumulation is responsible for the development of acute renal failure in ethylene glycol poisoning.1

There's more to see -- the rest of this entry is available only to subscribers.