Washington Manual of Medical Therapeutics
Oxazolidinones
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General Principles
Oxazolidinones block assembly of bacterial ribosomes and inhibit protein synthesis. These agents demonstrate high oral bioavailability, allowing for PO therapy when available, and do not require dose adjustments for hepatic or renal dysfunction.
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General Principles
Oxazolidinones block assembly of bacterial ribosomes and inhibit protein synthesis. These agents demonstrate high oral bioavailability, allowing for PO therapy when available, and do not require dose adjustments for hepatic or renal dysfunction.
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