Infective Endocarditis in Native or Prosthetic Valves

Infective Endocarditis in Native or Prosthetic Valves is a topic covered in the Washington Manual of Medical Therapeutics.

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  • Patient at risk or with suspected endocarditis should receive antibiotic therapy after two sets of blood cultures (Class I).1,2
  • These patients should be evaluated for need and timing of surgery: early surgery is recommended (Class I) for those with valve dysfunction causing heart 
failure, resistant organisms (fungi, staphylococcus), heart block/abscess, persistent infection.
  • Surgery is also recommended for relapsing prosthetic valve endocarditis (Class I).1,2
  • Those with large mobile vegetations of the native valve and recurrent emboli can be evaluated for early surgery (Class II).1,2

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  • Patient at risk or with suspected endocarditis should receive antibiotic therapy after two sets of blood cultures (Class I).1,2
  • These patients should be evaluated for need and timing of surgery: early surgery is recommended (Class I) for those with valve dysfunction causing heart 
failure, resistant organisms (fungi, staphylococcus), heart block/abscess, persistent infection.
  • Surgery is also recommended for relapsing prosthetic valve endocarditis (Class I).1,2
  • Those with large mobile vegetations of the native valve and recurrent emboli can be evaluated for early surgery (Class II).1,2

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