Glyphosate

Glyphosate is a topic covered in the Washington Manual of Medical Therapeutics.

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General Principles

Glyphosate is the most widely used herbicide in the world because of its broad-spectrum activity and its favorable safety profile. Glyphosate exerts its herbicidal activity by targeting a plant enzyme called 5-enolpyruvyl-shikimate-3-phosphate synthase (EPSPS).1

Epidemiology

According to the AAPCC there were 3181 acute glyphosate exposures in 2016, with 3 deaths reported.2 Additionally, the National Cancer Institute published its updated research in the Agricultural Health Study demonstrating that chronic exposures to glyphosate are not associated with the development of cancer.3

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General Principles

Glyphosate is the most widely used herbicide in the world because of its broad-spectrum activity and its favorable safety profile. Glyphosate exerts its herbicidal activity by targeting a plant enzyme called 5-enolpyruvyl-shikimate-3-phosphate synthase (EPSPS).1

Epidemiology

According to the AAPCC there were 3181 acute glyphosate exposures in 2016, with 3 deaths reported.2 Additionally, the National Cancer Institute published its updated research in the Agricultural Health Study demonstrating that chronic exposures to glyphosate are not associated with the development of cancer.3

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