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Introduction

Introduction is a topic covered in the Washington Manual of Medical Therapeutics.

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Cancer is one of leading causes of mortality both worldwide and in the United States, where approximately 610,000 deaths are estimated for 2018.1 The most common malignancies in the United States are lung cancer, prostate cancer, breast cancer, and colon cancer (Table 22-1). Cancer death rates have declined over the past decade owing to better uptake of screening strategies, advances in drug development, and availability of better supportive care. Improved understanding of the molecular pathways operative in cancer cells has led to the development of targeted agents, immunotherapy, and personalized treatment approaches associated with meaningful clinical benefit.

Table 22-1: Estimated New Cancer Cases and Rates of Death for Most Common Cancer Diagnoses in the United States for 2018
SitesNew CasesDeaths

Both SexesMaleFemaleTotal
Lung234,030121,680112,350154,050
Prostate164,690164,690
29,430
Breast268,6702550266,12041,400
Colon97,22049,96047,53050,630

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Citation

Williams, Dominique, et al., editors. "Introduction." Washington Manual of Medical Therapeutics, 35th ed., Wolters Kluwer Health, 2016. Washington Manual, www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602781/all/Introduction.
Introduction. In: Williams D, Ramgopal R, Gdowski M, et al, eds. Washington Manual of Medical Therapeutics. 35th ed. Wolters Kluwer Health; 2016. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602781/all/Introduction. Accessed August 21, 2019.
Introduction. (2016). In Williams, D., Ramgopal, R., Gdowski, M., Dretler, A., & Bhat, P. (Eds.), Washington Manual of Medical Therapeutics. Available from https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602781/all/Introduction
Introduction [Internet]. In: Williams D, Ramgopal R, Gdowski M, Dretler A, Bhat P, editors. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. [cited 2019 August 21]. Available from: https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602781/all/Introduction.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Introduction ID - 602781 ED - Williams,Dominique, ED - Ramgopal,Rajeev, ED - Gdowski,Mark, ED - Dretler,Alexandra, ED - Bhat,Pavat, BT - Washington Manual of Medical Therapeutics UR - https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602781/all/Introduction PB - Wolters Kluwer Health ET - 35 DB - Washington Manual DP - Unbound Medicine ER -