Washington Manual of Medical Therapeutics
Myeloproliferative Neoplasms
General Principles
MPNs are a group of hematologic malignancies characterized by clonal expansion of a hematopoietic stem cell resulting in overproduction of mature, largely functional cells. The 2016 World Health Organization (WHO) designated seven conditions as MPNs, including polycythemia vera (PV), essential thrombocythemia (ET) (discussed in Chapter 22, Cancer), CML (discussed in Chapter 22, Cancer), primary myelofibrosis (PMF), chronic neutrophilic leukemia, chronic eosinophilic leukemia, and MPN unclassifiable.1 The most common MPNs include PV, ET, CML, and PMF. This section will focus on PV and PMF.
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Citation
Bhat, Pavat, et al., editors. "Myeloproliferative Neoplasms." Washington Manual of Medical Therapeutics, 35th ed., Wolters Kluwer Health, 2016. The Washington Manual, www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602798/all/Myeloproliferative_Neoplasms.
Myeloproliferative Neoplasms. In: Bhat PP, Dretler AA, Gdowski MM, et al, eds. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602798/all/Myeloproliferative_Neoplasms. Accessed November 30, 2023.
Myeloproliferative Neoplasms. (2016). In Bhat, P., Dretler, A., Gdowski, M., Ramgopal, R., & Williams, D. (Eds.), Washington Manual of Medical Therapeutics (35th ed.). Wolters Kluwer Health. https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602798/all/Myeloproliferative_Neoplasms
Myeloproliferative Neoplasms [Internet]. In: Bhat PP, Dretler AA, Gdowski MM, Ramgopal RR, Williams DD, editors. Washington Manual of Medical Therapeutics. Wolters Kluwer Health; 2016. [cited 2023 November 30]. Available from: https://www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602798/all/Myeloproliferative_Neoplasms.
* Article titles in AMA citation format should be in sentence-case
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BT - Washington Manual of Medical Therapeutics
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PB - Wolters Kluwer Health
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