Uterine Cancer

Uterine Cancer is a topic covered in the Washington Manual of Medical Therapeutics.

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Epidemiology and Etiology

Uterine cancer is the most common gynecologic cancer in the US, with an increasing incidence estimated to account for 65,620 new cases and 12,590 deaths in 2020.1 Risk factors include obesity, early menarche, late menopause, nulliparity, diabetes mellitus, use of tamoxifen, and hereditary disorders such as Lynch syndrome. The risk is reduced with parity and the use of oral contraceptives. Most patients are perimenopausal or postmenopausal.

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Epidemiology and Etiology

Uterine cancer is the most common gynecologic cancer in the US, with an increasing incidence estimated to account for 65,620 new cases and 12,590 deaths in 2020.1 Risk factors include obesity, early menarche, late menopause, nulliparity, diabetes mellitus, use of tamoxifen, and hereditary disorders such as Lynch syndrome. The risk is reduced with parity and the use of oral contraceptives. Most patients are perimenopausal or postmenopausal.

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