Nonpurulent Skin and Soft-Tissue Infections (Erysipelas and Cellulitis)


General Principles

Erysipelas appears as a painful, superficial, erythematous, sharply demarcated lesion that usually affects the lower extremities. In normal hosts, GABHS is responsible for this infection.


Penicillin V 250–1000 mg PO q6h or penicillin G 1.0–2.0 million units IV q6h, depending on the severity of illness. In patients who are penicillin allergic, macrolides and clindamycin are alternatives.

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