Supportive Care

Supportive Care is a topic covered in the Washington Manual of Medical Therapeutics.

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Nausea and Vomiting

  • If nausea/vomiting occurs, chemotherapy-induced nausea and vomiting (CINV), as well as alternative etiologies such as bowel obstruction, brain metastasis, constipation and gastroenteritis, should be considered.
  • CINV can be categorized as acute (<24 hours) or delayed (>24 hours). Acute CINV is an important predictor of delayed CINV.
  • Commonly used antiemetic medications for prevention and management of CINV include dexamethasone, 5-hydroxytryptamine-3 (5-HT3) receptor antagonists (ondansetron, granisetron, dolasetron, palonosetron), neurokinin-1 receptor antagonists (aprepitant, fosaprepitant, etc.), prochlorperazine, anxiolytics (lorazepam), and olanzapine (atypical antipsychotic).

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Nausea and Vomiting

  • If nausea/vomiting occurs, chemotherapy-induced nausea and vomiting (CINV), as well as alternative etiologies such as bowel obstruction, brain metastasis, constipation and gastroenteritis, should be considered.
  • CINV can be categorized as acute (<24 hours) or delayed (>24 hours). Acute CINV is an important predictor of delayed CINV.
  • Commonly used antiemetic medications for prevention and management of CINV include dexamethasone, 5-hydroxytryptamine-3 (5-HT3) receptor antagonists (ondansetron, granisetron, dolasetron, palonosetron), neurokinin-1 receptor antagonists (aprepitant, fosaprepitant, etc.), prochlorperazine, anxiolytics (lorazepam), and olanzapine (atypical antipsychotic).

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