Washington Manual of Medical Therapeutics
Uncomplicated UTI Agents
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General Principles
Nitrofurantoin and oral fosfomycin are unique in their pharmacokinetic profiles, which result in high urinary, but minimal blood concentrations. These agents should only be used in the treatment of uncomplicated UTIs and should not be used for pyelonephritis or other systemic infections.
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General Principles
Nitrofurantoin and oral fosfomycin are unique in their pharmacokinetic profiles, which result in high urinary, but minimal blood concentrations. These agents should only be used in the treatment of uncomplicated UTIs and should not be used for pyelonephritis or other systemic infections.
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