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What is the role of dietary sodium and potassium in hypertension and target organ injury?
Am J Med Sci 1999; 317(3):152-9AJ

Abstract

There is substantial evidence from both observational epidemiology studies and randomized controlled trials that dietary intake of sodium and potassium is important in the etiology of hypertension. However, the direct evidence for a direct link between dietary sodium and potassium and risk of cardiovascular and renovascular events is limited. Epidemiological studies should be designed to examine the relationship between dietary intake of sodium and potassium and risk of stroke, coronary heart disease, left ventricular hypertrophy, and renal disease in a prospective manner. In these studies, dietary intake of sodium and potassium should be estimated using multiple 24-hour urine collections. These studies should be focused on African Americans because they are at a disproportionately high risk of developing hypertension and blood pressure-related vascular disease. Moreover, this group has been underrepresented in most previous epidemiological studies.

Authors+Show Affiliations

Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA. jhe@mailhost.tcs.tulane.eduNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.
Review

Language

eng

PubMed ID

10100688

Citation

He, J, and P K. Whelton. "What Is the Role of Dietary Sodium and Potassium in Hypertension and Target Organ Injury?" The American Journal of the Medical Sciences, vol. 317, no. 3, 1999, pp. 152-9.
He J, Whelton PK. What is the role of dietary sodium and potassium in hypertension and target organ injury? Am J Med Sci. 1999;317(3):152-9.
He, J., & Whelton, P. K. (1999). What is the role of dietary sodium and potassium in hypertension and target organ injury? The American Journal of the Medical Sciences, 317(3), pp. 152-9.
He J, Whelton PK. What Is the Role of Dietary Sodium and Potassium in Hypertension and Target Organ Injury. Am J Med Sci. 1999;317(3):152-9. PubMed PMID: 10100688.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - What is the role of dietary sodium and potassium in hypertension and target organ injury? AU - He,J, AU - Whelton,P K, PY - 1999/4/1/pubmed PY - 1999/4/1/medline PY - 1999/4/1/entrez SP - 152 EP - 9 JF - The American journal of the medical sciences JO - Am. J. Med. Sci. VL - 317 IS - 3 N2 - There is substantial evidence from both observational epidemiology studies and randomized controlled trials that dietary intake of sodium and potassium is important in the etiology of hypertension. However, the direct evidence for a direct link between dietary sodium and potassium and risk of cardiovascular and renovascular events is limited. Epidemiological studies should be designed to examine the relationship between dietary intake of sodium and potassium and risk of stroke, coronary heart disease, left ventricular hypertrophy, and renal disease in a prospective manner. In these studies, dietary intake of sodium and potassium should be estimated using multiple 24-hour urine collections. These studies should be focused on African Americans because they are at a disproportionately high risk of developing hypertension and blood pressure-related vascular disease. Moreover, this group has been underrepresented in most previous epidemiological studies. SN - 0002-9629 UR - https://www.unboundmedicine.com/medline/citation/10100688/full_citation L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9629(15)40497-5 DB - PRIME DP - Unbound Medicine ER -