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Adult nutrient intake as a risk factor for Parkinson's disease.
Int J Epidemiol 1999; 28(6):1102-9IJ

Abstract

BACKGROUND

This population-based case-control study evaluated nutrient intake as a risk factor for Parkinson's disease (PD) among people aged > or =50 years in metropolitan Detroit.

METHODS

Cases (n = 126) were diagnosed between 1991 and 1995 and neurologist-confirmed. Controls (n = 432) were frequency-matched for sex, age (+/-5 years) and race. Using a standardized food frequency questionnaire, subjects reported the foods they ate within the past year.

RESULTS

Estimating the association between PD and risk of being in the highest versus the lowest intake quartile, there were elevated odds ratios for total fat (OR 1.94, 95% confidence interval [CI] : 1.05-3.58), cholesterol (OR 2.11, 95% CI: 1.14-3.90), lutein (OR 2.52, 95% CI: 1.32-4.84) and iron (OR 1.88, 95% CI: 1.05-3.38).

CONCLUSIONS

These results suggest an association of PD with high intake of total fat, saturated fats, cholesterol, lutein and iron.

Authors+Show Affiliations

Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, Michigan, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

10661654

Citation

Johnson, C C., et al. "Adult Nutrient Intake as a Risk Factor for Parkinson's Disease." International Journal of Epidemiology, vol. 28, no. 6, 1999, pp. 1102-9.
Johnson CC, Gorell JM, Rybicki BA, et al. Adult nutrient intake as a risk factor for Parkinson's disease. Int J Epidemiol. 1999;28(6):1102-9.
Johnson, C. C., Gorell, J. M., Rybicki, B. A., Sanders, K., & Peterson, E. L. (1999). Adult nutrient intake as a risk factor for Parkinson's disease. International Journal of Epidemiology, 28(6), pp. 1102-9.
Johnson CC, et al. Adult Nutrient Intake as a Risk Factor for Parkinson's Disease. Int J Epidemiol. 1999;28(6):1102-9. PubMed PMID: 10661654.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Adult nutrient intake as a risk factor for Parkinson's disease. AU - Johnson,C C, AU - Gorell,J M, AU - Rybicki,B A, AU - Sanders,K, AU - Peterson,E L, PY - 2000/2/8/pubmed PY - 2000/3/4/medline PY - 2000/2/8/entrez SP - 1102 EP - 9 JF - International journal of epidemiology JO - Int J Epidemiol VL - 28 IS - 6 N2 - BACKGROUND: This population-based case-control study evaluated nutrient intake as a risk factor for Parkinson's disease (PD) among people aged > or =50 years in metropolitan Detroit. METHODS: Cases (n = 126) were diagnosed between 1991 and 1995 and neurologist-confirmed. Controls (n = 432) were frequency-matched for sex, age (+/-5 years) and race. Using a standardized food frequency questionnaire, subjects reported the foods they ate within the past year. RESULTS: Estimating the association between PD and risk of being in the highest versus the lowest intake quartile, there were elevated odds ratios for total fat (OR 1.94, 95% confidence interval [CI] : 1.05-3.58), cholesterol (OR 2.11, 95% CI: 1.14-3.90), lutein (OR 2.52, 95% CI: 1.32-4.84) and iron (OR 1.88, 95% CI: 1.05-3.38). CONCLUSIONS: These results suggest an association of PD with high intake of total fat, saturated fats, cholesterol, lutein and iron. SN - 0300-5771 UR - https://www.unboundmedicine.com/medline/citation/10661654/full_citation L2 - https://academic.oup.com/ije/article-lookup/doi/10.1093/ije/28.6.1102 DB - PRIME DP - Unbound Medicine ER -