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Lichen amyloidosus: a bullous variant.
Ann Acad Med Singap. 2000 Jan; 29(1):105-7.AA

Abstract

INTRODUCTION

Lichen amyloidosus is a common skin disease seen among Asian patients.

CLINICAL PICTURE

Typical features range from macular hyperpigmentation to pruritic, lichenified, hyperpigmented papules. However, in this rare bullous variant of lichen amyloidosus, bullae and vesicles are present. Histopathologically, deposits of amyloid were seen in the papillary dermis, associated with an intraepidermal or subepidermal blister.

TREATMENT AND OUTCOME

No good treatment so far, but pruritus can be relieved by topical steroid.

CONCLUSION

It is important to screen for systemic amyloidosis with the relevant investigations as it can present similarly with blistering eruptions, in which the prognosis would be grave.

Authors+Show Affiliations

National Skin Centre, Singapore.No affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

10748976

Citation

Khoo, B P., and Y K. Tay. "Lichen Amyloidosus: a Bullous Variant." Annals of the Academy of Medicine, Singapore, vol. 29, no. 1, 2000, pp. 105-7.
Khoo BP, Tay YK. Lichen amyloidosus: a bullous variant. Ann Acad Med Singap. 2000;29(1):105-7.
Khoo, B. P., & Tay, Y. K. (2000). Lichen amyloidosus: a bullous variant. Annals of the Academy of Medicine, Singapore, 29(1), 105-7.
Khoo BP, Tay YK. Lichen Amyloidosus: a Bullous Variant. Ann Acad Med Singap. 2000;29(1):105-7. PubMed PMID: 10748976.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Lichen amyloidosus: a bullous variant. AU - Khoo,B P, AU - Tay,Y K, PY - 2000/4/5/pubmed PY - 2000/5/8/medline PY - 2000/4/5/entrez SP - 105 EP - 7 JF - Annals of the Academy of Medicine, Singapore JO - Ann Acad Med Singap VL - 29 IS - 1 N2 - INTRODUCTION: Lichen amyloidosus is a common skin disease seen among Asian patients. CLINICAL PICTURE: Typical features range from macular hyperpigmentation to pruritic, lichenified, hyperpigmented papules. However, in this rare bullous variant of lichen amyloidosus, bullae and vesicles are present. Histopathologically, deposits of amyloid were seen in the papillary dermis, associated with an intraepidermal or subepidermal blister. TREATMENT AND OUTCOME: No good treatment so far, but pruritus can be relieved by topical steroid. CONCLUSION: It is important to screen for systemic amyloidosis with the relevant investigations as it can present similarly with blistering eruptions, in which the prognosis would be grave. SN - 0304-4602 UR - https://www.unboundmedicine.com/medline/citation/10748976/Lichen_amyloidosus:_a_bullous_variant_ L2 - https://medlineplus.gov/amyloidosis.html DB - PRIME DP - Unbound Medicine ER -