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Physiologic and related behavioral outcomes from the Women's Lifestyle Heart Trial.

Abstract

The Women's Lifestyle Heart Trial was a small (N = 28) randomized controlled trial to evaluate the effects of a comprehensive lifestyle self-management program (very low-fat vegetarian diet, stress-management training, exercise, group support, and smoking cessation) on reduction of cardiovascular risk factors in postmenopausal women with coronary heart disease (CHD). Women assigned to the treatment condition (Prime Time) participated in a week-long retreat followed by twice-weekly 4-hour meetings. Endpoints were program adherence; changes in lipid profiles, body mass, blood pressure, hypolipidemic and antihypertensive medications; and quality of life. Risk factor and psychosocial evaluations were conducted at baseline and at 4, 12, and 24 months. Repeated measures analyses of covariance revealed that the dietary, stress management, and physical activity changes made by intervention women were dramatic and lasting. There were significantly greater improvements in the Prime Time condition compared to the usual care control group on body mass, angina symptoms, and quality of life, and a tendency for a greater reduction in blood pressure-lowering medications. Similar patterns were seen in lipids, blood pressure, and lipid-lowering medications, but did not reach significance. These results demonstrate that postmenopausal CHD women can make lasting lifestyle changes, and that these changes may reduce the need for cardiac medications and improve CHD risk factors and quality of life.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Chronic Illness Research Group, Oregon Research Institute, Eugene 97403-1983, USA.

    ,

    Source

    MeSH

    Aged
    Blood Pressure
    Body Weight
    Cardiovascular Agents
    Coronary Disease
    Diet, Fat-Restricted
    Exercise
    Female
    Humans
    Life Style
    Lipids
    Middle Aged
    Oregon
    Postmenopause
    Quality of Life
    Risk Factors
    Smoking Cessation
    Social Support
    Stress, Psychological
    Survival Analysis
    Treatment Outcome
    Women's Health

    Pub Type(s)

    Clinical Trial
    Journal Article
    Randomized Controlled Trial
    Research Support, U.S. Gov't, P.H.S.

    Language

    eng

    PubMed ID

    10892523

    Citation

    Toobert, D J., et al. "Physiologic and Related Behavioral Outcomes From the Women's Lifestyle Heart Trial." Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine, vol. 22, no. 1, 2000, pp. 1-9.
    Toobert DJ, Glasgow RE, Radcliffe JL. Physiologic and related behavioral outcomes from the Women's Lifestyle Heart Trial. Ann Behav Med. 2000;22(1):1-9.
    Toobert, D. J., Glasgow, R. E., & Radcliffe, J. L. (2000). Physiologic and related behavioral outcomes from the Women's Lifestyle Heart Trial. Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine, 22(1), pp. 1-9.
    Toobert DJ, Glasgow RE, Radcliffe JL. Physiologic and Related Behavioral Outcomes From the Women's Lifestyle Heart Trial. Ann Behav Med. 2000;22(1):1-9. PubMed PMID: 10892523.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Physiologic and related behavioral outcomes from the Women's Lifestyle Heart Trial. AU - Toobert,D J, AU - Glasgow,R E, AU - Radcliffe,J L, PY - 2000/7/13/pubmed PY - 2001/2/28/medline PY - 2000/7/13/entrez SP - 1 EP - 9 JF - Annals of behavioral medicine : a publication of the Society of Behavioral Medicine JO - Ann Behav Med VL - 22 IS - 1 N2 - The Women's Lifestyle Heart Trial was a small (N = 28) randomized controlled trial to evaluate the effects of a comprehensive lifestyle self-management program (very low-fat vegetarian diet, stress-management training, exercise, group support, and smoking cessation) on reduction of cardiovascular risk factors in postmenopausal women with coronary heart disease (CHD). Women assigned to the treatment condition (Prime Time) participated in a week-long retreat followed by twice-weekly 4-hour meetings. Endpoints were program adherence; changes in lipid profiles, body mass, blood pressure, hypolipidemic and antihypertensive medications; and quality of life. Risk factor and psychosocial evaluations were conducted at baseline and at 4, 12, and 24 months. Repeated measures analyses of covariance revealed that the dietary, stress management, and physical activity changes made by intervention women were dramatic and lasting. There were significantly greater improvements in the Prime Time condition compared to the usual care control group on body mass, angina symptoms, and quality of life, and a tendency for a greater reduction in blood pressure-lowering medications. Similar patterns were seen in lipids, blood pressure, and lipid-lowering medications, but did not reach significance. These results demonstrate that postmenopausal CHD women can make lasting lifestyle changes, and that these changes may reduce the need for cardiac medications and improve CHD risk factors and quality of life. SN - 0883-6612 UR - https://www.unboundmedicine.com/medline/citation/10892523/full_citation L2 - https://academic.oup.com/abm/article-lookup/doi/10.1007/BF02895162 DB - PRIME DP - Unbound Medicine ER -