Tags

Type your tag names separated by a space and hit enter

Chronic exercise training effects on immune function.

Abstract

PURPOSE

This paper reviews the recent literature on the chronic effects of exercise training on immune function in humans. There is a general perception by athletes and other physically active individuals that regular moderate activity enhances, whereas intense exercise suppresses, resistance to minor illnesses such as upper respiratory tract infection (URTI). This perception is supported by epidemiological data in endurance athletes and limited data from intervention studies using moderate exercise in previously untrained individuals. The apparently high incidence of URTI among endurance athletes has prompted interest the relationship between chronic exercise training and immune function. Whereas immune cell number is generally normal during intense exercise training, recent evidence suggests that prolonged periods of intense training may lead to slight impairment in immune parameters such as neutrophil function, serum and mucosal immunoglobulin levels, plasma glutamine concentration, and possibly natural killer cell cytotoxic activity. In contrast. moderate exercise training has either no effect on, or may stimulate, these immune parameters.

CONCLUSION

Whereas athletes are not clinically immune deficient, it is possible that the combined effects of small changes in several immune parameters may compromise resistance to minor illnesses such as URTI. Strategies to prevent URTI in athletes include avoiding overtraining, providing adequate rest and recovery during the training cycle and after competition, limiting exposure to sources of infection, ensuring adequate nutrition, and possibly vitamin C supplementation. It is uncertain at present whether moderate exercise training is helpful in preventing infectious illness among the wider population.

Links

  • Publisher Full Text
  • Authors+Show Affiliations

    School of Human Movement Studies, The University of Queensland, Brisbane, Australia. laurel@hms.uq.edu.au

    Source

    Medicine and science in sports and exercise 32:7 Suppl 2000 Jul pg S369-76

    MeSH

    Antibody Formation
    Ascorbic Acid
    Exercise
    Humans
    Immunity, Cellular
    Nutritional Status
    Physical Endurance
    Respiratory Tract Infections
    Sports

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    10910293

    Citation

    Mackinnon, L T.. "Chronic Exercise Training Effects On Immune Function." Medicine and Science in Sports and Exercise, vol. 32, no. 7 Suppl, 2000, pp. S369-76.
    Mackinnon LT. Chronic exercise training effects on immune function. Med Sci Sports Exerc. 2000;32(7 Suppl):S369-76.
    Mackinnon, L. T. (2000). Chronic exercise training effects on immune function. Medicine and Science in Sports and Exercise, 32(7 Suppl), pp. S369-76.
    Mackinnon LT. Chronic Exercise Training Effects On Immune Function. Med Sci Sports Exerc. 2000;32(7 Suppl):S369-76. PubMed PMID: 10910293.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Chronic exercise training effects on immune function. A1 - Mackinnon,L T, PY - 2000/7/26/pubmed PY - 2001/2/28/medline PY - 2000/7/26/entrez SP - S369 EP - 76 JF - Medicine and science in sports and exercise JO - Med Sci Sports Exerc VL - 32 IS - 7 Suppl N2 - PURPOSE: This paper reviews the recent literature on the chronic effects of exercise training on immune function in humans. There is a general perception by athletes and other physically active individuals that regular moderate activity enhances, whereas intense exercise suppresses, resistance to minor illnesses such as upper respiratory tract infection (URTI). This perception is supported by epidemiological data in endurance athletes and limited data from intervention studies using moderate exercise in previously untrained individuals. The apparently high incidence of URTI among endurance athletes has prompted interest the relationship between chronic exercise training and immune function. Whereas immune cell number is generally normal during intense exercise training, recent evidence suggests that prolonged periods of intense training may lead to slight impairment in immune parameters such as neutrophil function, serum and mucosal immunoglobulin levels, plasma glutamine concentration, and possibly natural killer cell cytotoxic activity. In contrast. moderate exercise training has either no effect on, or may stimulate, these immune parameters. CONCLUSION: Whereas athletes are not clinically immune deficient, it is possible that the combined effects of small changes in several immune parameters may compromise resistance to minor illnesses such as URTI. Strategies to prevent URTI in athletes include avoiding overtraining, providing adequate rest and recovery during the training cycle and after competition, limiting exposure to sources of infection, ensuring adequate nutrition, and possibly vitamin C supplementation. It is uncertain at present whether moderate exercise training is helpful in preventing infectious illness among the wider population. SN - 0195-9131 UR - https://www.unboundmedicine.com/medline/citation/10910293/full_citation L2 - http://Insights.ovid.com/pubmed?pmid=10910293 DB - PRIME DP - Unbound Medicine ER -