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The effects of alcohol consumption upon the gastrointestinal tract.

Abstract

Regardless of the type and dose of beverage involved, alcohol facilitates the development of gastroesophageal reflux disease by reducing the pressure of the lower esophageal sphincter and esophageal motility. Fermented and nondistilled alcoholic beverages increase gastrin levels and acid secretion. Succinic and maleic acid contained in certain alcoholic drinks also stimulate acid secretion. Low alcohol doses accelerate gastric emptying, whereas high doses delay emptying and slow bowel motility. Alcohol facilitates the development of superficial gastritis and chronic atrophic gastritis--though it has not been shown to cause peptic ulcer. Alcoholic beverages, fundamentally wine, have important bactericidal effects upon Helicobacter pylori and enteropathogenic bacteria. The main alcohol-related intestinal alterations are diarrhea and malabsorption, with recovery after restoring a normal diet. Alcohol facilitates the development of oropharyngeal, esophageal, gastric, and colon cancer. Initial research suggests that wine may be comparatively less carcinogenic.

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  • Publisher Full Text
  • Authors+Show Affiliations

    Department of Gastroenterology, San Eloy Hospital, Baracaldo, Spain.

    Source

    MeSH

    Alcohol Drinking
    Alcoholic Beverages
    Bacterial Infections
    Digestive System Neoplasms
    Gastritis
    Gastroesophageal Reflux
    Gastrointestinal Motility
    Humans
    Intestinal Absorption
    Wine

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    11151864

    Citation

    Bujanda, L. "The Effects of Alcohol Consumption Upon the Gastrointestinal Tract." The American Journal of Gastroenterology, vol. 95, no. 12, 2000, pp. 3374-82.
    Bujanda L. The effects of alcohol consumption upon the gastrointestinal tract. Am J Gastroenterol. 2000;95(12):3374-82.
    Bujanda, L. (2000). The effects of alcohol consumption upon the gastrointestinal tract. The American Journal of Gastroenterology, 95(12), pp. 3374-82.
    Bujanda L. The Effects of Alcohol Consumption Upon the Gastrointestinal Tract. Am J Gastroenterol. 2000;95(12):3374-82. PubMed PMID: 11151864.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - The effects of alcohol consumption upon the gastrointestinal tract. A1 - Bujanda,L, PY - 2001/1/11/pubmed PY - 2001/2/28/medline PY - 2001/1/11/entrez SP - 3374 EP - 82 JF - The American journal of gastroenterology JO - Am. J. Gastroenterol. VL - 95 IS - 12 N2 - Regardless of the type and dose of beverage involved, alcohol facilitates the development of gastroesophageal reflux disease by reducing the pressure of the lower esophageal sphincter and esophageal motility. Fermented and nondistilled alcoholic beverages increase gastrin levels and acid secretion. Succinic and maleic acid contained in certain alcoholic drinks also stimulate acid secretion. Low alcohol doses accelerate gastric emptying, whereas high doses delay emptying and slow bowel motility. Alcohol facilitates the development of superficial gastritis and chronic atrophic gastritis--though it has not been shown to cause peptic ulcer. Alcoholic beverages, fundamentally wine, have important bactericidal effects upon Helicobacter pylori and enteropathogenic bacteria. The main alcohol-related intestinal alterations are diarrhea and malabsorption, with recovery after restoring a normal diet. Alcohol facilitates the development of oropharyngeal, esophageal, gastric, and colon cancer. Initial research suggests that wine may be comparatively less carcinogenic. SN - 0002-9270 UR - https://www.unboundmedicine.com/medline/citation/11151864/full_citation L2 - http://Insights.ovid.com/pubmed?pmid=11151864 DB - PRIME DP - Unbound Medicine ER -