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Reflux symptoms are associated with psychiatric disease.

Abstract

AIMS

To evaluate the frequency of reflux symptoms in patients with a diagnosed psychiatric disorder and to assess potential risk factors for symptom occurrence.

METHODS

The presence of reflux symptoms was compared between a case population of 94 psychiatric patients and a control population of 198 non-psychiatric patients.

RESULTS

Heartburn, exercise-induced heartburn, cough and dysphagia were all reported significantly more frequently by subjects with psychiatric disorders than by control subjects. The presence of any psychiatric diagnosis exerted an increased risk for both heartburn (odds ratio, 2.71; 95% confidence interval, 1.01-7.30) and exercise-induced heartburn (3.34; 1.12-9.96). The type of psychiatric disorder, the type of psychotropic medication and the lifestyle did not influence the presence of reflux symptoms.

CONCLUSIONS

Reflux symptoms occur more frequently in patients with than without a diagnosed psychiatric disorder. The reflux symptoms are not associated with any specific type of medication and may reflect a generally reduced threshold for or distorted perception of symptoms.

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  • Authors+Show Affiliations

    ,

    Department of Veterans Affairs Medical Center, Albuquerque, NM 87108, USA.

    , ,

    Source

    Alimentary pharmacology & therapeutics 15:12 2001 Dec pg 1907-12

    MeSH

    Adult
    Aged
    Alcohol Drinking
    Case-Control Studies
    Deglutition Disorders
    Female
    Gastroesophageal Reflux
    Heartburn
    Humans
    Male
    Mental Disorders
    Middle Aged
    Odds Ratio
    Risk Factors
    Smoking
    United States

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    11736721

    Citation

    Avidan, B, et al. "Reflux Symptoms Are Associated With Psychiatric Disease." Alimentary Pharmacology & Therapeutics, vol. 15, no. 12, 2001, pp. 1907-12.
    Avidan B, Sonnenberg A, Giblovich H, et al. Reflux symptoms are associated with psychiatric disease. Aliment Pharmacol Ther. 2001;15(12):1907-12.
    Avidan, B., Sonnenberg, A., Giblovich, H., & Sontag, S. J. (2001). Reflux symptoms are associated with psychiatric disease. Alimentary Pharmacology & Therapeutics, 15(12), pp. 1907-12.
    Avidan B, et al. Reflux Symptoms Are Associated With Psychiatric Disease. Aliment Pharmacol Ther. 2001;15(12):1907-12. PubMed PMID: 11736721.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Reflux symptoms are associated with psychiatric disease. AU - Avidan,B, AU - Sonnenberg,A, AU - Giblovich,H, AU - Sontag,S J, PY - 2001/12/12/pubmed PY - 2002/4/16/medline PY - 2001/12/12/entrez SP - 1907 EP - 12 JF - Alimentary pharmacology & therapeutics JO - Aliment. Pharmacol. Ther. VL - 15 IS - 12 N2 - AIMS: To evaluate the frequency of reflux symptoms in patients with a diagnosed psychiatric disorder and to assess potential risk factors for symptom occurrence. METHODS: The presence of reflux symptoms was compared between a case population of 94 psychiatric patients and a control population of 198 non-psychiatric patients. RESULTS: Heartburn, exercise-induced heartburn, cough and dysphagia were all reported significantly more frequently by subjects with psychiatric disorders than by control subjects. The presence of any psychiatric diagnosis exerted an increased risk for both heartburn (odds ratio, 2.71; 95% confidence interval, 1.01-7.30) and exercise-induced heartburn (3.34; 1.12-9.96). The type of psychiatric disorder, the type of psychotropic medication and the lifestyle did not influence the presence of reflux symptoms. CONCLUSIONS: Reflux symptoms occur more frequently in patients with than without a diagnosed psychiatric disorder. The reflux symptoms are not associated with any specific type of medication and may reflect a generally reduced threshold for or distorted perception of symptoms. SN - 0269-2813 UR - https://www.unboundmedicine.com/medline/citation/11736721/full_citation L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0269-2813&date=2001&volume=15&issue=12&spage=1907 DB - PRIME DP - Unbound Medicine ER -