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Relation of adult lifestyle and socioeconomic factors to the prevalence of Helicobacter pylori infection.

Abstract

INTRODUCTION

The influence of adult socioeconomic status, co-habitation, gender, smoking, coffee and alcohol intake on risk of Helicobacter pylori infection is uncertain.

METHODS

Subjects between aged 40-49 years were randomly invited to attend their local primary care centre. Participants were interviewed by a researcher on smoking, coffee and alcohol intake, history of living with a partner, present and childhood socioeconomic conditions. Helicobacter pylori status was determined by 13C-urea breath test.

RESULTS

In all, 32 929 subjects were invited, 8429 (26%) were eligible and 2327 (27.6%) were H. pylori positive. Helicobacter pylori infection was more common in men and this association remained after controlling for childhood and adult risk factors in a logistic regression model (odds ratio [OR] = 1.15; 95% CI: 1.03-1.29). Living with a partner was also an independent risk factor for infection (OR = 1.30; 95% CI: 1.01-1.67), particularly in partners of lower social class (social class IV and V-OR = 1.47; 95% CI: 1.19-1.81, compared with social class I and II). Helicobacter pylori infection was more common in lower social class groups (I and II-22% infected, III-29% infected, IV and V-38% infected) and there was a significant increase in risk of infection in manual workers compared with non-manual workers after controlling for other risk factors (OR = 1.18; 95% CI: 1.03-1.34). Alcohol and coffee intake were not independent risk factors for infection and smoking was only a risk factor in those smoking >35 cigarettes a day.

CONCLUSIONS

Male gender, living with a partner and poor adult socioeconomic conditions are associated with increased risk of H. pylori infection.

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  • Authors+Show Affiliations

    ,

    Centre for Digestive Diseases, The General Infirmary at Leeds, UK. paulmo@ulth.northy.nhs.uk

    , , , , , , , ,

    Source

    MeSH

    Adult
    Cross-Sectional Studies
    England
    Female
    Helicobacter Infections
    Helicobacter pylori
    Humans
    Life Style
    Logistic Models
    Male
    Marital Status
    Middle Aged
    Odds Ratio
    Prevalence
    Risk Factors
    Social Class
    Socioeconomic Factors

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    12055165

    Citation

    Moayyedi, Paul, et al. "Relation of Adult Lifestyle and Socioeconomic Factors to the Prevalence of Helicobacter Pylori Infection." International Journal of Epidemiology, vol. 31, no. 3, 2002, pp. 624-31.
    Moayyedi P, Axon AT, Feltbower R, et al. Relation of adult lifestyle and socioeconomic factors to the prevalence of Helicobacter pylori infection. Int J Epidemiol. 2002;31(3):624-31.
    Moayyedi, P., Axon, A. T., Feltbower, R., Duffett, S., Crocombe, W., Braunholtz, D., ... Forman, D. (2002). Relation of adult lifestyle and socioeconomic factors to the prevalence of Helicobacter pylori infection. International Journal of Epidemiology, 31(3), pp. 624-31.
    Moayyedi P, et al. Relation of Adult Lifestyle and Socioeconomic Factors to the Prevalence of Helicobacter Pylori Infection. Int J Epidemiol. 2002;31(3):624-31. PubMed PMID: 12055165.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Relation of adult lifestyle and socioeconomic factors to the prevalence of Helicobacter pylori infection. AU - Moayyedi,Paul, AU - Axon,Anthony T R, AU - Feltbower,Richard, AU - Duffett,Sara, AU - Crocombe,Will, AU - Braunholtz,David, AU - Richards,I D Gerald, AU - Dowell,Anthony C, AU - Forman,David, AU - ,, PY - 2002/6/11/pubmed PY - 2002/9/18/medline PY - 2002/6/11/entrez SP - 624 EP - 31 JF - International journal of epidemiology JO - Int J Epidemiol VL - 31 IS - 3 N2 - INTRODUCTION: The influence of adult socioeconomic status, co-habitation, gender, smoking, coffee and alcohol intake on risk of Helicobacter pylori infection is uncertain. METHODS: Subjects between aged 40-49 years were randomly invited to attend their local primary care centre. Participants were interviewed by a researcher on smoking, coffee and alcohol intake, history of living with a partner, present and childhood socioeconomic conditions. Helicobacter pylori status was determined by 13C-urea breath test. RESULTS: In all, 32 929 subjects were invited, 8429 (26%) were eligible and 2327 (27.6%) were H. pylori positive. Helicobacter pylori infection was more common in men and this association remained after controlling for childhood and adult risk factors in a logistic regression model (odds ratio [OR] = 1.15; 95% CI: 1.03-1.29). Living with a partner was also an independent risk factor for infection (OR = 1.30; 95% CI: 1.01-1.67), particularly in partners of lower social class (social class IV and V-OR = 1.47; 95% CI: 1.19-1.81, compared with social class I and II). Helicobacter pylori infection was more common in lower social class groups (I and II-22% infected, III-29% infected, IV and V-38% infected) and there was a significant increase in risk of infection in manual workers compared with non-manual workers after controlling for other risk factors (OR = 1.18; 95% CI: 1.03-1.34). Alcohol and coffee intake were not independent risk factors for infection and smoking was only a risk factor in those smoking >35 cigarettes a day. CONCLUSIONS: Male gender, living with a partner and poor adult socioeconomic conditions are associated with increased risk of H. pylori infection. SN - 0300-5771 UR - https://www.unboundmedicine.com/medline/citation/12055165/full_citation L2 - https://academic.oup.com/ije/article-lookup/doi/10.1093/ije/31.3.624 DB - PRIME DP - Unbound Medicine ER -