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Frequent nut intake and risk of death from coronary heart disease and all causes in postmenopausal women: the Iowa Women's Health Study.

Abstract

BACKGROUND AND AIM

Recent epidemiological studies suggest that there is an inverse association between the frequent consumption of nuts and the risk of coronary heart disease (CHD), and clinical investigations suggest that diets high in nuts may reduce serum cholesterol levels. This study assessed whether the risk of death due to CHD and all causes is reduced in postmenopausal women who frequently consume nuts.

METHODS AND RESULTS

In 1986, 34,111 postmenopausal women with no known cardiovascular disease reported the frequency of their consumption of nuts and other foods, as well as other CHD risk factors. During approximately 12 years of follow-up, 3726 women died, 657 from CHD. After adjustment for multiple risk factors for CHD and dietary variables, there was an inverse but not statistically significant association between frequent nut consumption (two or more 28.5 g servings per week compared with less than one serving per month) and death from CHD (relative risk 0.81; 95% confidence interval: 0.60-1.11). There was also a weak inverse association between frequent nut intake and all-cause mortality (relative risk 0.88; 95% confidence interval: 0.77-0.99, p for trend = 0.047).

CONCLUSIONS

Frequent nut consumption may offer postmenopausal women modest protection against the risk of death from all causes and CHD.

Authors+Show Affiliations

,

Division of Epidemiology, School of Public Health, University of Minnesota, 1300 South Second Street, Suite 300, Minneapolis, MN 55454-1015, USA.

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Source

MeSH

Aged
Cohort Studies
Coronary Disease
Diet
Female
Follow-Up Studies
Food, Organic
Humans
Middle Aged
Nuts
Postmenopause
Risk Factors
Surveys and Questionnaires
United States

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

12055701

Citation

Ellsworth, J L., et al. "Frequent Nut Intake and Risk of Death From Coronary Heart Disease and All Causes in Postmenopausal Women: the Iowa Women's Health Study." Nutrition, Metabolism, and Cardiovascular Diseases : NMCD, vol. 11, no. 6, 2001, pp. 372-7.
Ellsworth JL, Kushi LH, Folsom AR. Frequent nut intake and risk of death from coronary heart disease and all causes in postmenopausal women: the Iowa Women's Health Study. Nutr Metab Cardiovasc Dis. 2001;11(6):372-7.
Ellsworth, J. L., Kushi, L. H., & Folsom, A. R. (2001). Frequent nut intake and risk of death from coronary heart disease and all causes in postmenopausal women: the Iowa Women's Health Study. Nutrition, Metabolism, and Cardiovascular Diseases : NMCD, 11(6), pp. 372-7.
Ellsworth JL, Kushi LH, Folsom AR. Frequent Nut Intake and Risk of Death From Coronary Heart Disease and All Causes in Postmenopausal Women: the Iowa Women's Health Study. Nutr Metab Cardiovasc Dis. 2001;11(6):372-7. PubMed PMID: 12055701.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Frequent nut intake and risk of death from coronary heart disease and all causes in postmenopausal women: the Iowa Women's Health Study. AU - Ellsworth,J L, AU - Kushi,L H, AU - Folsom,A R, PY - 2002/6/12/pubmed PY - 2002/8/16/medline PY - 2002/6/12/entrez SP - 372 EP - 7 JF - Nutrition, metabolism, and cardiovascular diseases : NMCD JO - Nutr Metab Cardiovasc Dis VL - 11 IS - 6 N2 - BACKGROUND AND AIM: Recent epidemiological studies suggest that there is an inverse association between the frequent consumption of nuts and the risk of coronary heart disease (CHD), and clinical investigations suggest that diets high in nuts may reduce serum cholesterol levels. This study assessed whether the risk of death due to CHD and all causes is reduced in postmenopausal women who frequently consume nuts. METHODS AND RESULTS: In 1986, 34,111 postmenopausal women with no known cardiovascular disease reported the frequency of their consumption of nuts and other foods, as well as other CHD risk factors. During approximately 12 years of follow-up, 3726 women died, 657 from CHD. After adjustment for multiple risk factors for CHD and dietary variables, there was an inverse but not statistically significant association between frequent nut consumption (two or more 28.5 g servings per week compared with less than one serving per month) and death from CHD (relative risk 0.81; 95% confidence interval: 0.60-1.11). There was also a weak inverse association between frequent nut intake and all-cause mortality (relative risk 0.88; 95% confidence interval: 0.77-0.99, p for trend = 0.047). CONCLUSIONS: Frequent nut consumption may offer postmenopausal women modest protection against the risk of death from all causes and CHD. SN - 0939-4753 UR - https://www.unboundmedicine.com/medline/citation/12055701/full_citation L2 - http://www.diseaseinfosearch.org/result/130 DB - PRIME DP - Unbound Medicine ER -